* {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
}

.genetica-container {
    font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, sans-serif;
}

.genetica-container .container {
    max-width: 1200px;
    margin: 0 auto;
    background: white;
    border-radius: 20px;
    box-shadow: 0 20px 60px rgba(0,0,0,0.3);
    overflow: hidden;
}

.genetica-container .header {
    background: linear-gradient(135deg, #667eea 0%, #764ba2 100%);
    color: white;
    padding: 30px;
    text-align: center;
    position: relative;
}

.genetica-container .header h1 {
    font-size: 28px;
    margin-bottom: 10px;
}

.genetica-container .header p {
    opacity: 0.9;
    font-size: 14px;
}

.genetica-container .content {
    padding: 30px;
}

.genetica-container .section {
    margin-bottom: 30px;
    padding: 25px;
    background: #f8f9fa;
    border-radius: 12px;
    border-left: 4px solid #667eea;
}

.genetica-container .section-title {
    font-size: 20px;
    color: #333;
    margin-bottom: 20px;
    font-weight: 600;
}

.genetica-container .form-group {
    margin-bottom: 20px;
}

.genetica-container label {
    display: block;
    margin-bottom: 8px;
    color: #000;
    font-weight: 700;
    font-size: 14px;
}

.genetica-container select, 
.genetica-container input[type="number"], 
.genetica-container input[type="text"] {
    width: 100%;
    padding: 12px;
    border: 2px solid #e0e0e0;
    border-radius: 8px;
    font-size: 14px;
    transition: all 0.3s;
}

.genetica-container select:focus, 
.genetica-container input:focus {
    outline: none;
    border-color: #667eea;
    box-shadow: 0 0 0 3px rgba(102, 126, 234, 0.1);
}

.genetica-container .checkbox-group {
    display: flex;
    flex-wrap: wrap;
    gap: 15px;
}

.genetica-container .checkbox-item {
    display: flex;
    align-items: center;
    padding: 10px 15px;
    background: white;
    border: 2px solid #e0e0e0;
    border-radius: 8px;
    cursor: pointer;
    transition: all 0.3s;
}

.genetica-container .checkbox-item:hover {
    border-color: #667eea;
    background: #f0f4ff;
}

.genetica-container .checkbox-item input[type="checkbox"] {
    width: auto;
    margin-right: 8px;
    cursor: pointer;
}

.genetica-container .radio-group {
    display: flex;
    flex-wrap: wrap;
    gap: 15px;
}

.genetica-container .radio-item {
    display: flex;
    align-items: center;
    padding: 10px 15px;
    background: white;
    border: 2px solid #e0e0e0;
    border-radius: 8px;
    cursor: pointer;
    transition: all 0.3s;
}

.genetica-container .radio-item:hover {
    border-color: #667eea;
    background: #f0f4ff;
}

.genetica-container .radio-item input[type="radio"] {
    width: auto;
    margin-right: 8px;
    cursor: pointer;
}

.genetica-container .btn {
    background: linear-gradient(135deg, #667eea 0%, #764ba2 100%);
    color: white;
    padding: 15px 30px;
    border: none;
    border-radius: 8px;
    font-size: 16px;
    font-weight: 600;
    cursor: pointer;
    transition: all 0.3s;
    width: 100%;
    margin-top: 20px;
}

.genetica-container .btn:hover {
    transform: translateY(-2px);
    box-shadow: 0 10px 20px rgba(102, 126, 234, 0.3);
}

.genetica-container .btn:active {
    transform: translateY(0);
}

.genetica-container .result {
    display: none;
    margin-top: 30px;
    padding: 25px;
    border-radius: 12px;
    animation: slideIn 0.5s ease;
}

@keyframes slideIn {
    from {
        opacity: 0;
        transform: translateY(20px);
    }
    to {
        opacity: 1;
        transform: translateY(0);
    }
}

.genetica-container .result.indicado {
    background: #d4edda;
    border-left: 4px solid #28a745;
}

.genetica-container .result.no-indicado {
    background: #f8d7da;
    border-left: 4px solid #dc3545;
}

.genetica-container .result.valorar {
    background: #fff3cd;
    border-left: 4px solid #ffc107;
}

.genetica-container .result-title {
    font-size: 22px;
    font-weight: 600;
    margin-bottom: 15px;
    color: #333;
}

.genetica-container .result-content {
    font-size: 15px;
    line-height: 1.6;
    color: #555;
}

.genetica-container .genes-panel {
    margin-top: 20px;
    padding: 20px;
    background: white;
    border-radius: 8px;
    border: 2px solid #e0e0e0;
}

.genetica-container .genes-panel h3 {
    font-size: 18px;
    margin-bottom: 15px;
    color: #333;
}

.genetica-container .genes-list {
    display: flex;
    flex-wrap: wrap;
    gap: 8px;
}

.genetica-container .gene-tag {
    background: #667eea;
    color: white;
    padding: 6px 12px;
    border-radius: 20px;
    font-size: 13px;
    font-weight: 500;
}

.genetica-container .evidence-badge {
    display: inline-block;
    padding: 4px 10px;
    border-radius: 4px;
    font-size: 12px;
    font-weight: 600;
    margin-top: 10px;
}

.genetica-container .evidence-fuerte {
    background: #28a745;
    color: white;
}

.genetica-container .evidence-debil {
    background: #ffc107;
    color: #333;
}

.genetica-container .info-box {
    background: #e7f3ff;
    border-left: 4px solid #2196F3;
    padding: 15px;
    margin-top: 15px;
    border-radius: 8px;
    font-size: 14px;
    line-height: 1.6;
}

.genetica-container .criteria-list {
    margin-top: 15px;
    padding-left: 20px;
}

.genetica-container .criteria-list li {
    margin-bottom: 8px;
    line-height: 1.5;
}

.genetica-container .hidden {
    display: none;
}

.genetica-container .tab-container {
    display: flex;
    gap: 10px;
    margin-bottom: 20px;
    border-bottom: 2px solid #e0e0e0;
}

.genetica-container .tab {
    padding: 12px 24px;
    background: transparent;
    border: none;
    border-bottom: 3px solid transparent;
    cursor: pointer;
    font-size: 15px;
    font-weight: 500;
    color: #666;
    transition: all 0.3s;
}

.genetica-container .tab.active {
    color: #667eea;
    border-bottom-color: #667eea;
}

.genetica-container .tab:hover {
    color: #667eea;
}

.genetica-container .tab-content {
    display: none;
}

.genetica-container .tab-content.active {
    display: block !important;
}

@media (max-width: 768px) {
    .genetica-container .content {
        padding: 20px;
    }

    .genetica-container .section {
        padding: 20px;
    }

    .genetica-container .header h1 {
        font-size: 24px;
    }

    .genetica-container .tab-container {
        flex-wrap: wrap;
    }

    .genetica-container .tab {
        flex: 1;
        min-width: 150px;
    }
}

.genetica-container.footer {
    background: #f0f2f5;
    border-top: 1px solid #e0e0e0;
    padding: 20px 30px;
    text-align: center;
    font-size: 13px;
    color: #888;
    line-height: 1.6;
}

.genetica-container.footer a {
    color: #667eea;
    text-decoration: none;
    border-bottom: 1px solid transparent;
    transition: border-color 0.2s;
}

.genetica-container.footer a:hover {
    border-bottom-color: #667eea;
}