Asociación Española
de Gastroenterología
Enfermedad Inflamatoria Intestinal

Pilar Nos Mateu
Coordinador

El Grupo de Trabajo de Enfermedad Inflamatoria Intestinal de la AEG está formado mayoritariamente por miembros del Grupo Español de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa (GETECCU). Es objetivo primordial del grupo el estudio y la investigación de la Enfermedad Inflamatoria Intestinal (EII): enfermedad de Crohn y colitis ulcerosa y la homologación de criterios clínico-terapéuticos en el diagnóstico y tratamiento de la misma.


Epidemiological Risk Factors in Microscopic Colitis. A Prospective Case Control Study
49

Autores:
Fernández-Bañares F, de Sousa MR, Salas A, Beltrán B, Piqueras M, Iglesias E, Gisbert JP, Lobo B, Puig-Diví V, García-Planella E, Ordás I, Andreu M, Calvo M, Montoro M, Esteve M, Viver JM; for the RECOMINA Project, GETECCU (Grupo Español de Enfermedades de Crohn y Colitis Ulcerosa). Referencia: Inflamm Bowel Dis. 2013 Feb;19(2):411-417.

BACKGROUND:
The cause of collagenous colitis (CC) and lymphocytic colitis (LC) is unknown and epidemiological risk factors for CC and LC are not well studied. The aim was to evaluate in a case-control study epidemiological risk factors for CC and LC.

METHODS:
In all, 120 patients with CC, 70 with CL, and 128 controls were included. For all cases and controls information was prospectively recorded. A binary logistic regression analysis was performed separately for CC and LC.

RESULTS:
Independent associations observed with the diagnosis of CC were: current smoking (odds ratio [OR], 2.4), history of polyarthritis (OR, 20.8), and consumption of lansoprazole (OR, 6.4), low-dose aspirin (OR, 3.8), beta-blockers (OR, 3.6), and angiotensin II receptor antagonists (OR 0.20). In the case of LC they were: current smoking (OR, 3.8), associated autoimmune diseases (OR, 8), and consumption of sertraline (OR, 17.5), omeprazole (OR 2.7), low-dose aspirin (OR, 4.7), and oral antidiabetic drugs (OR, 0.14).

CONCLUSIONS:
The consumption of drugs, current smoking, and associated autoimmune diseases were independently associated with the risk of microscopic colitis.