Asociación Española
de Gastroenterología
Enfermedad Inflamatoria Intestinal

Pilar Nos Mateu
Coordinador

El Grupo de Trabajo de Enfermedad Inflamatoria Intestinal de la AEG está formado mayoritariamente por miembros del Grupo Español de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa (GETECCU). Es objetivo primordial del grupo el estudio y la investigación de la Enfermedad Inflamatoria Intestinal (EII): enfermedad de Crohn y colitis ulcerosa y la homologación de criterios clínico-terapéuticos en el diagnóstico y tratamiento de la misma.


Therapeutic guidelines on ulcerative colitis. A GRADE methodology based effort of GETECCU
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Autores: Gomollón F, García-López S, Sicilia B, Gisbert JP, Hinojosa J. Referencia: Gastroenterol Hepatol. 2013 Feb;36(2):104-14. doi: 10.1016/j.gastrohep.2012.09.006. Epub 2013 Jan 14.

BACKGROUND AND AIM:
Evidence-based clinical guidelines on Ulcerative colitis (UC) have been developed through a consensus, while GRADE methodology is the current standard for guideline development. This is the first one based on GRADE methodology on UC.

METHODS:
Following GRADE methodology, the Spanish Group of Ulcerative Colitis and Crohn's disease (GETECCU) have developed a guideline on UC treatment. After selection of relevant clinical scenarios, 32 clinical questions were chosen and recommendations were established.

RESULTS:
In 2 questions no recommendation was possible. Twenty-two actions were recommended for, 14 strongly and 8 weakly. However, in 8 questions a recommendation against doing something was obtained, weak in 5 and strong in 3. The majority of recommendations were based on moderate quality evidence, and only 5 on high-quality evidence.

CONCLUSIONS:
With GRADE methodology we find a clear recommendation on possible actions in most clinical decisions in UC treatment, but much more clinical high-quality research is needed.